A young neurologist, Dr. Callie Wallace, returns to her hometown of Sperling, Texas, with business partner and friend Dr. Richard Cortez to set up their neurology practice. The unexpected death of one of Callie's patients throws the overachieving physician into a tailspin, and she begins to question her own sanity. Her mother wants to be there for her daughter, but a dark family secret keeps their relationship contentious and distant. A long-time boyfriend also wants to be there for Callie, but she keeps him at arm's length and repeatedly turns to Richard, causing strain. It all comes down to who exactly Callie can trust...definitely not herself.